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Clinical Trials
September 20, 2021

Retina Foundation is Major Center for Next Phase of Gene Therapy for X-Linked Retinitis Pigmentosa: SKYLINE

X-linked retinitis pigmentosa (XLRP) is an inherited eye disease that causes gradual vision loss in boys and young men. The disease begins with night blindness and a progressive loss of peripheral vision. This disease eventually leads to central vision loss and results in a person becoming legally blind in their 40s. The Retina Foundation has […]

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Clinical Trials
June 29, 2021

Assessing Mobility Vision and Retinitis Pigmentosa

Scientists in the Rose-Silverthorne Retinal Degeneration Laboratory at the Retina Foundation recently began a new clinical trial utilizing a mobility course. The course is designed to assess mobility and functional vision in patients with retinitis pigmentosa (RP), an inherited eye disease characterized by gradual vision loss of peripheral and night vision. This mobility course, created by […]

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Clinical Research
May 15, 2020

In-Depth Vision Evaluations & Research Updates for Retinal Diseases – Video Update

Yi-Zhong Wang, Ph.D., Director, Macular Function Laboratory, discusses visual function and imaging evaluation for patients with retinal diseases and his deep machine learning project in the video update below. This update is relevant for those interested in learning more about our research for age-related macular degeneration, diabetic retinopathy, and other inherited eye diseases. Should you […]

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Patient Resource
April 9, 2020

Retina Foundation 20/20 Video Research Updates

The Retina Foundation is pleased to share 20/20 video updates as we continue to move forward with our cutting-edge research, reading, planning experiments, analyzing data, and drafting new grant proposals as we telecommute. Introduction Video by Dr. Karl Csaky, CEO – April 9, 2020 Clinical Research in Age-Related Macular Degeneration – April 10, 2020 Investigating […]

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Clinical Trials
October 1, 2019

Promising Results From Ongoing Phase 1/2 Clinical Trial for X-Linked Retinitis Pigmentosa (XLRP)

The Retina Foundation of the Southwest is one of four U.S. centers conducting a Phase 1/2 dose escalation, gene replacement trial for x-linked retinitis pigmentosa (XLRP). On September 26th, the clinical trial sponsor, Applied Genetic Technologies Corporation (AGTC) announced the initial results. Investigators from all four research sites have begun seeing encouraging signs of benefit […]

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Clinical Trials
July 23, 2019

Gene Therapy Trial for Choroideremia

In a clinical research study headed by Dr. David Birch, scientists in the Rose-Silverthorne Retinal Degenerations Lab are testing the efficacy of gene therapy in patients with choroideremia. This late stage trial is based on early Phase 1 studies where over 90% of treated patients maintained or improved their vision over a one-year follow-up period. […]

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News/ Press Release
July 19, 2019

FFB Pledges $300,000 to Support Dr. Yi-Zhong Wang’s Artificial Intelligence/ Deep Machine Learning Project

Yi-Zhong Wang, Ph.D., Scientific Director, Macular Function Laboratory, is working to achieve automatic and accurate identification of defects in the structure of patients’ retinas by applying deep machine learning method. Over the past year, using a cutting-edge computer system, Dr. Wang has been training a deep convolutional neural network model to learn how to detect […]

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