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Clinical Trials
September 20, 2021

Retina Foundation is Major Center for Next Phase of Gene Therapy for X-Linked Retinitis Pigmentosa: SKYLINE

X-linked retinitis pigmentosa (XLRP) is an inherited eye disease that causes gradual vision loss in boys and young men. The disease begins with night blindness and a progressive loss of peripheral vision. This disease eventually leads to central vision loss and results in a person becoming legally blind in their 40s. The Retina Foundation has […]

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Clinical Trials
August 26, 2021

Age-Related Macular Degeneration Happenings at the Foundation

At the Retina Foundation, our Laboratory Directors often partner with various pharmaceutical and biotechnology companies to conduct clinical trials and research. In our Clinical Center of Innovation for Age-Related Macular Degeneration (AMD), led by Karl Csaky, M.D., Ph.D., Chief Executive and Medical Officer of the Foundation, we currently have 15 studies for AMD and geographic […]

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Clinical Trials
June 29, 2021

Assessing Mobility Vision and Retinitis Pigmentosa

Scientists in the Rose-Silverthorne Retinal Degeneration Laboratory at the Retina Foundation recently began a new clinical trial utilizing a mobility course. The course is designed to assess mobility and functional vision in patients with retinitis pigmentosa (RP), an inherited eye disease characterized by gradual vision loss of peripheral and night vision. This mobility course, created by […]

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Clinical Trials
October 1, 2019

Promising Results From Ongoing Phase 1/2 Clinical Trial for X-Linked Retinitis Pigmentosa (XLRP)

The Retina Foundation of the Southwest is one of four U.S. centers conducting a Phase 1/2 dose escalation, gene replacement trial for x-linked retinitis pigmentosa (XLRP). On September 26th, the clinical trial sponsor, Applied Genetic Technologies Corporation (AGTC) announced the initial results. Investigators from all four research sites have begun seeing encouraging signs of benefit […]

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Clinical Trials
July 23, 2019

Gene Therapy Trial for Choroideremia

In a clinical research study headed by Dr. David Birch, scientists in the Rose-Silverthorne Retinal Degenerations Lab are testing the efficacy of gene therapy in patients with choroideremia. This late stage trial is based on early Phase 1 studies where over 90% of treated patients maintained or improved their vision over a one-year follow-up period. […]

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Clinical Trials
November 7, 2018

Phase III Treatment Trial for Stargardt Disease Enrolls First Patient

The Retina Foundation of the Southwest was the first site in the world to enroll patients in a new international Phase III Clinical Treatment Trial for Stargardt Disease sponsored by the clinical-stage ophthalmology company Acucela. This study is a phase III treatment trial to evaluate Acucela’s leading drug candidate, emixustat hydrochloride (“emixustat”), as a treatment […]

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